| 中文名 | 亚油酸 |
| 英文名 | Linoleic acid |
| 中文别名 | - |
| 英文别名 | - |
| 来源 | 亚麻Linum usitatissimum L. |
| 化合物类型 | 脂肪族类（Aliphatics）>不饱和脂肪酸 |
| 化学式 | C18H32O2 |
| 分子量 | 280.45 |
| CAS号 | 60-33-3 |
| 纯度 | 98%, HPLC |
| 溶剂/溶解度 | DMSO: ≥ 43.33 mg/ml (154.50 mM) |
| 溶液配制 | 5mg加入1.78ml DMSO，或者每2.80mg加入1ml DMSO，配制成10mM溶液。 |
| 产品描述 | Linoleic acid is a common polyunsaturated (PUFA) found in plant-based oils, nuts and seeds. Linoleic acid is a part of membrane phospholipids, and functions as a structural component to maintain a certain level of membrane fluidity of the transdermal water barrier of the epidermis. Linoleic acid induces red blood cells and hemoglobin damage via oxidative mechanism. | ||||
| 信号通路 | Oxidation | ||||
| 靶点 | - | - | - | - | - |
| IC50 | - | - | - | - | - |
| 体外研究 | Linoleic acid contains unsaturated double bonds that are highly vulnerable to free radical attack and oxidation. If ROS are produced in great quantities, the body can no longer efficiently remove them. In such instances, ROS may be released into the extracellular space, causing damage to surrounding cells and tissues. Linoleic acid is a decomposition product of a free fatty acid and has been linked to erythrocyte damage. | ||||
| 体内研究 | N/A | ||||
| 临床实验 | NCT02063802: Obesity, Phase 2; NCT00706745: Atherosclerosis, Phase 3; NCT00204932: Obesity, Phase 2. | ||||
1.Jay Whelan. Linoleic Acid. Adv Nutr. 2013,4(3):311-312.
2.Yuan T, et al. Int J Clin Exp Pathol. 2015,8(5):5044-52.
包装清单：| 产品编号 | 产品名称 | 包装 |
| SM9092-25mg | 亚油酸(98%, HPLC) | 25mg |
| SM9092-100mg | 亚油酸(98%, HPLC) | 100mg |
| － | 说明书 | 1份 |
-20℃避光保存，至少一年有效。
注意事项：本产品可能对人体有一定的毒害作用，请注意适当防护，以避免直接接触人体或吸入体内。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。
