| CAS Number | Chemical Formula | Molecular Weight | Purity | Grade |
| 2023788-19-2 | C225H348N48O68 | ~4813.2 | ≥98.0% | BioReagent |
基本信息(General Information)：
| Name (Chinese) | 替尔泊肽 |
| Name (English) | Tirzepatide |
| Specifications | BioReagent |
| Chemical Formula | C225H348N48O68 |
| Synonym (Chinese) | 替西帕肽；新型双重GIP/GLP-1激动剂 |
| Synonym (English) | Mounjaro (Tirzepatide); LY-3298176; LY3298176 |
| Sequence (Three-Letter Code) |
Tyr-{Aib}-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Ile-{Aib}-Leu-Asp-Lys-Ile-Ala-Gln-{diacid-C20-gamma-Glu-(AEEA)2-Lys}-Ala-Phe-Val-Gln-Trp-Leu-Ile-Ala-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-NH2 |
| Sequence (One-Letter Code) |
Y-{Aib}-EGTFTSDYSI-{Aib}-LDKIAQ-{C20 diacid-gamma-Glu-(AEEA)2-Lys}-AFVQWLIAGGPSSGAPPPS-NH2 |
| Source | Synthetic |
| Reconstitution | Ultrapure water: ＞10mg/ml or refer to the relevant literatures |
产品描述(Description)：
| Application | Tirzepatide is a Glucose-dependent Insulinotropic Polypeptide Receptor Agonist and GLP-1 Receptor Agonist. The mechanism of action of tirzepatide is as a G-Protein-linked Receptor Interaction and Glucagon-like Peptide-1 (GLP-1) Agonist. |
| General description | Tirzepatide and Semaglutide have similar sequences, with the lys side chain in the sequence modified with PEG, which is a functional group of the peptide and can increase the water solubility of the sequence. The main physiological function of tirzepatide is a double agonist of glucose dependent insulin nutritional polypeptide (GIP) and glucagon like peptide-1 (GLP-1) receptor, which is used to treat type 2 diabetes [1-2]. |
性质(Properties)：
| Form | White powder |
| Solubility | Soluble in water |
安全信息(Safety Information)：
| Hazard Pictogram Codes | - |
| Signal Word | - |
| Hazard Statements | - |
| Precautionary Statements | - |
| Personal Protective Equipment | - |
| Hazard Codes (Europe) | - |
| Risk Codes (Europe) | - |
| Safety Codes (Europe) | - |
| RIDADR | - |
| WGK Germany | - |
| RTECS | - |
| Flash Point (F) | - |
| Flash Point (C) | - |
| 产品编号 | 产品名称 | 包装 |
| P9089-5mg | Tirzepatide (BioReagent) | 5mg |
| P9089-25mg | Tirzepatide (BioReagent) | 25mg |
| P9089-100mg | Tirzepatide (BioReagent) | 100mg |
| － | 说明书 | 1份 |
-20ºC避光保存，一年有效。
注意事项：本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。
参考文献：1.Dhillon S. Semaglutide: First Global Approval. Drugs. 2018. 78(2):275-284.
2.Marso SP, Bain SC, Consoli A, Eliaschewitz FG, et al. N Engl J Med. 2016. 375(19):1834-1844.
相关产品：| 产品编号 | 产品名称 | 包装 |
| P9085 | Semaglutide (司美格鲁肽, BioReagent) | 5/25/100mg |
| P9087 | Semaglutide Intermediate P29 (司美格鲁肽中间体P29) | 5/25/100mg |
| P9089 | Tirzepatide (替尔泊肽, BioReagent) | 5/25/100mg |
