CAS Number | Chemical Formula | Molecular Weight | Purity | Grade |
2058-46-0 | C22H24N2O9·HCl | 496.90 | Reagent grade |
基本信息(General Information):
|
产品描述(Description):
Application | Chemical structure: tetracycline |
Application | Oxytetracycline is a tetracycline analog isolated from the actinomycete Streptomyces rimosus. Oxytetracycline is an antibiotic indicated for treatment of infections caused by Gram positive and Gram negative microorganisms such as Mycoplasma pneumoniae, Pasteurella pestis, Escherichia coli, Haemophilus influenzae, and Diplococcus pneumoniae. It is used in studies on the oxytetracycline-resistance gene (otrA). Oxytetracycline hydrochloride is used to study phagosome-lysosome (P-L) fusion in P388D1 cells and antibiotic susceptibilities of Mycoplasma bovis isolates. |
Biochem/physiol Actions | Oxytetracycline inhibits translation which results in cell death. It binds to the 30S ribosomal subunit and prevents the amino-acyl tRNA from binding to the A site of the ribosome. The binding is reversible in nature. Oxytetracycline is lipophilic so it can easily pass through a cell membrane and passively diffuses through channels in the bacterial membrane. Mode of Action: Inhibits protein synthesis (elongation) by preventing binding of aminoacyl-tRNA to the 30S subunit. Antimicrobial spectrum: Gram-negative and Gram-positive bacteria. Mode of Resistance: Active efflux, ribosome protection, tetracycline inactivation. |
Other Notes | 10g,50g,100g Keep container tightly closed in a dry and well-ventilated place.Store under inert gas. Light sensitive.Air sensitive. |
性质(Properties):
form | 粉末或晶体 |
color | 黄色 |
solubility | 易溶于水,略溶于乙醇(96%)。水溶液静置后会变浑浊。 |
impurities | 杂质总量≤3.5%(相关物质(HPLC)) |
Mode of action | 蛋白合成 | 干扰 |
antibiotic activity spectrum | 革兰氏阴性菌 革兰氏阳性菌 |
安全信息(Safety Information):
Hazard Pictogram Codes | GHS08,GHS09 |
Signal Word | Warning |
Hazard Statements | H361d - H411 |
Precautionary Statements | P201 - P202 - P273 - P280 - P308 + P313 - P391 |
Personal Protective Equipment | Eyeshields, Gloves, type N95 (US) |
Hazard Codes (Europe) | - |
Risk Codes (Europe) | - |
Safety Codes (Europe) | - |
RIDADR | NONH for all modes of transport |
WGK Germany | 2 |
RTECS | QI8225000 |
Flash Point (F) | - |
Flash Point (C) | - |
产品编号 | 产品名称 | 包装 |
ST2551-5g | 盐酸土霉素(Reagent grade) | 5g |
ST2551-25g | 盐酸土霉素(Reagent grade) | 25g |
ST2551-100g | 盐酸土霉素(Reagent grade) | 100g |
— | 说明书 | 1份 |
室温保存,四年有效。
注意事项:本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
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