| CAS Number | Chemical Formula | Molecular Weight | Purity | Grade |
| 11028-71-0 | - | 102kDa | >90% | BioReagent |
基本信息(General Information)：
| Name (Chinese) | 伴刀豆球蛋白A |
| Name (English) | Concanavalin A |
| Specifications | BioReagent, type IV |
| Chemical Formula | - |
| Synonym (Chinese) | 刀豆球蛋白A，刀豆凝集素A，刀豆素A |
| Synonym (English) | ConA, Con A |
| Beilstein Registry No. | - |
| EINECS Number | 234-258-2 |
| MDL Number | MFCD00071069 |
| UNSPSC Code | - |
产品描述(Description)：
| Application | ConA binds specifically to α-Mannose、α-Galactose structures found in sugars, glycoproteins and glycolipids. ConA is a T cell mitogen that can activate the immune system, recruit lymphocytes and elicit cytokine production [1]. In addition to its mitogenic activity, ConA can induce programmed cell death via mitochondria-mediated apoptosis and autophagy [2-4]. Also, ConA has been reported to activate NFAT (Nuclear factor of activated T cells), a family of transcription factors that are important in the development and function of the immune system, including T cell receptor engagement [5]. Immobilized Con A has been used in affinity chromatography purifications of a wide variety of glycoproteins and cellular structures. |
| General description | Concanavalin A (ConA) lectin is isolated from Jack beans (Canavalia ensiformis) and purified by affinity chromatography. It has broad applicability and is the most widely used lectin within molecular biology research. The identity is determined by SDS-PAGE and the protein content by spectrophotometry. The molecular weight of the lectin is 102kDa, and the molecular weight of its monomer is 25.5kDa. Polyacrylamide gel electrophoresis in SDS of ConA yields three major bands corresponding to molecular weights 27, 13 and 10kDa. One minor band is visible at 18kDa. |
性质(Properties)：
| Appearance | White lyophilized powder or flocculate. |
| Form | Lyophilized powder from a buffer containing 0.5mM MnCl2, 0.5mM CaCl2, no preservatives are added. |
| Reconstitution | ConA may be reconstituted with ≥1mg/ml of PBS (pH7.4) or 0.9% sodium chloride solution before use. Spin the vial gently until full dissolution. Aggregation is thought to occur in the presence of high concentrations of 2-mercaptoethanol. In absence of lactose the lectin will polymerize and storage at pH8.6-8.8 causes precipitation. |
| Potency | ConA reacts with a number of bacterial and animal cells and can distinguish between certain normal and tumor cells. It can initiate cell division (mitogenesis). ≤40μg per ml agglutination activity. |
| Microorganisms | <100 CFU/g |
| Protein content | >90% protein by OD280nm (ε 1mg/ml=1.14), essentially salt free. |
| Storage temp. | -20ºC |
安全信息(Safety Information)：
| Hazard Pictogram Codes | GHS08 |
| Signal Word | Danger |
| Hazard Statements | H317-H334-H361 |
| Precautionary Statements | P201-P202-P280-P302 + P352-P304 + P340 + P312-P308 + P313 |
| Personal Protective Equipment | dust mask type N95 (US), Eyeshields, Gloves |
| Hazard Codes (Europe) | - |
| Risk Codes (Europe) | - |
| Safety Codes (Europe) | - |
| RIDADR | - |
| WGK Germany | WGK 3 |
| RTECS | GK6890000 |
| Flash Point (F) | - |
| Flash Point (C) | - |
| 产品编号 | 产品名称 | 包装 |
| ST2062-25mg | 伴刀豆球蛋白A (ConA) (BioReagent) | 25mg |
| ST2062-100mg | 伴刀豆球蛋白A (ConA) (BioReagent) | 100mg |
| ST2062-500mg | 伴刀豆球蛋白A (ConA) (BioReagent) | 500mg | － | 说明书 | 1份 |
-20ºC保存，三年有效。
注意事项：本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。
| 产品编号 | 产品名称 | 包装 |
| P2156-5ml | BeyoMag™ Concanavalin A Magnetic Beads (刀豆素A磁珠) | 5ml |
| P2156-1ml | BeyoMag™ Concanavalin A Magnetic Beads (刀豆素A磁珠) | 1ml |
| P2156-200μl | BeyoMag™ Concanavalin A Magnetic Beads (刀豆素A磁珠) | 200μl |
| ST2062-25mg | 伴刀豆球蛋白A (ConA) (BioReagent) | 25mg |
| ST2062-100mg | 伴刀豆球蛋白A (ConA) (BioReagent) | 100mg |
| ST2062-500mg | 伴刀豆球蛋白A (ConA) (BioReagent) | 500mg |
