化学信息：
| 中文名 | 槲皮苷 |
| 英文名 | Quercitrin |
| 中文别名 | 槲皮甙；橡皮甙；榭黄甙；栎素 |
| 英文别名 | 3-rhamnosyl quercetin; Quercitroside; Quercitronic acid; Thujin; Quercetin 3-rhamnoside |
| 来源 | 合欢Albizia julibrissin Durazz.；地耳草Hypericum japonicum Thunb. ex Murray |
| 化合物类型 | 黄酮类(Flavonoids)>黄酮>黄酮醇 |
| 化学式 | C21H20O11 |
| 分子量 | 448.38 |
| CAS号 | 522-12-3 |
| 纯度 | 98%, HPLC |
| 溶剂/溶解度 | DMSO: ≥ 31 mg/ml (69.14 mM) |
| 溶液配制 | 10mg加入1.12ml DMSO，或者每4.48mg加入1ml DMSO，配制成10mM溶液。 |
生物信息
| 产品描述 | Quercitrin is a natural compound found in Tartary buckwheat with a potential anti-inflammation effect that is used to treat heart and vascular conditions. | ||||
| 信号通路 | Inflammation | ||||
| 靶点 | Caspase-3 | MMP | - | - | - |
| IC50 | - | - | - | - | - |
| 体外研究 | There were significant increases in caspase-3 activity, loss of MMP, and increases in the apoptotic cell population in response to quercitrin in DLD-1 colon cancer cells in a time- and dose-dependent manner. | ||||
| 体内研究 | ICR mice received CCl4 intraperitoneally with or without quercitrin co-administration for 4 weeks. Data showed that quercitrin significantly suppressed the elevation of reactive oxygen species (ROS) production and malondialdehyde (MDA) content, reduced tissue plasminogen activator (t-PA) activity, enhanced the antioxidant enzyme activities and abrogated cytochrome P450 2E1 (CYP2E1) induction in mouse brains. | ||||
| 临床实验 | N/A | ||||
1. Cincin ZB, et al. Pathol Oncol Res. 2015,21(2):333-8.
2. Ma JQ, et al. Food Funct. 2016,7(1):549-56.
3. Li W, et al. Am J Physiol Renal Physiol. 2016,311(1):F217-26.
包装清单：| 产品编号 | 产品名称 | 包装 |
| SM2143-10mM | 槲皮苷(98%, HPLC) | 10mM×0.2ml |
| SM2143-5mg | 槲皮苷(98%, HPLC) | 5mg |
| SM2143-25mg | 槲皮苷(98%, HPLC) | 25mg |
| SM2143-100mg | 槲皮苷(98%, HPLC) | 100mg |
| - | 说明书 | 1份 |
-20℃避光保存，至少一年有效。固体粉末4℃避光保存，至少一个月有效。如果溶于非DMSO溶剂，建议分装后-80℃避光保存，预计6个月内有效。
注意事项：本产品可能对人体有一定的毒害作用，请注意适当防护，以避免直接接触人体或吸入体内。
本产品仅限于专业人员的科学研究用，不得用于临床诊断或治疗，不得用于食品或药品，不得存放于普通住宅内。
为了您的安全和健康，请穿实验服并戴一次性手套操作。
