Ionomycin (钙离子载体)
收藏
产品编号 S1672-5mg
数量
¥ 4193.00
产品包装:
5mM×0.05ml 5mM×0.2ml 5mg
产品简介
使用说明
相关文件下载
相关产品
相关论文
产品问答

本Ionomycin为Ionomycin calcium,是一种常用的钙离子载体,可以高度选择性结合钙离子(Ca2+>Mg2+>>Ba2+),并且比A23187的效果要好很多。Ionomycin在pH7.0和9.5直接可以结合钙离子,并产生较强的紫外吸收。
Ionomycin常用于转运钙离子穿过各种生物膜。加入Ionomycin最常用于提高细胞内的钙离子水平。通过提高细胞内钙离子水平,Ionomycin可以诱导神经细胞发生细胞凋亡,可以诱导一些细胞产生cell cycle arrest,也可以产生多种由于细胞内钙离子水平升高而产生的其它生物功能。
Ionomycin分子量为747.07,分子式为C41H70CaO9,CAS Number:56092-82-1。本产品纯度大于98%。
本Ionomycin为进口分装,其中5mM包装产品用DMSO配制,有0.05ml和0.2ml两种包装。5mg包装为粉末装。
包装清单:

产品编号 产品名称 包装
S1672-250nmol Ionomycin (钙离子载体) 5mM×0.05ml
S1672-1μmol Ionomycin (钙离子载体) 5mM×0.2ml
S1672-5mg Ionomycin (钙离子载体) 5mg
说明书 1份

保存条件:
-20℃避光保存,一年有效。
注意事项:
本产品对人体有害,操作时请小心,并注意有效防护以避免直接接触人体或吸入体内。
本Ionomycin在4℃、冰浴等较低温度情况下会凝固而粘在离心管管底、管壁或管盖内,可以20-25℃水浴温育片刻至全部融解后使用。
本产品仅限于专业人员的科学研究用,不得用于临床诊断或治疗,不得用于食品或药品,不得存放于普通住宅内。
为了您的安全和健康,请穿实验服并戴一次性手套操作。

使用说明:
1. Ionomycin常见使用浓度范围为1-10μM。具体的最佳工作浓度请参考相关文献,或根据实验目的,以及所培养的特定细胞和组织,通过实验进行摸索和优化。
相关产品请点击如下按钮:
使用本产品的文献:
1. Liu Z, Cai Y, Wang Y, Nie Y, Zhang C, Xu Y, Zhang X, Lu Y, Wang Z, Poo M, Sun Q.
Cell 2018 Feb 8;172(4):881-887.e7. (IF 38.637)
2. Liu Z, Cai Y, Wang Y, Nie Y, Zhang C, Xu Y, Zhang X, Lu Y, Wang Z, Poo M, Sun Q.
Cell. 172(4):881-887.e7. (IF 38.637)
3. Yanrui Yang, Jiang Chen, Xue Chen, Di Li, Jianfeng He, Shen Wang, Shun Zhao, Xiaoyu Yang, Shikun Deng, Chunfang Tong, Dou Wang, Zhenzhen Guo, Dong Li, Cong Ma, Xin Liang, Yun S Shi, Jia-Jia Liu
J Cell Biol. doi: 10.1083/jcb.202007172. (IF 8.811)
4. Yang C, Qin Y, Jiang D, Chen HY.
ACS APPL MATER INTER 2016 Aug 10;8(31):19892-8. (IF 8.758)
5. Yong T, Hu J, Zhang X, Li F, Yang H, Gan L, Yang X.
ACS APPL MATER INTER 2016 Oct 5. [Epub ahead of print] (IF 8.758)
6. Yu Chen, Qiaomei Cai, Chaohu Pan, Wancheng Liu, Lili Li, Junxiao Liu, Meiling Gao, Xiaorong Li, Liguo Wang, Yu Rao, Heng Yang, Genhong Cheng
Cancer Immunol Res. doi: 10.1158/2326-6066.CIR-21-0806. (IF 8.728)
7. Bali Zhao, Jingyi Yang, Bing He, Xian Li, Hu Yan, Shuning Liu, Yi Yang, Dihan Zhou, Bowen Liu, Xuxu Fan, Maohua Zhong, Ejuan Zhang, Fan Zhang, Yue Zhang, Yao-Qing Chen, Shibo Jiang, Huimin Yan
Cell Rep. doi: 10.1016/j.celrep.2021.109401. (IF 8.109)
8. Jingyu Ni, Hao Zhang, Xiaodan Wang, Zhihao Liu, Tong Nie, Lan Li, Jing Su, Yan Zhu, Chuanrui Ma, Yuting Huang, Jingyuan Mao, Xiumei Gao, Guanwei Fan
Cell Death Dis. doi: 10.1038/s41419-022-05516-y. (IF 6.304)
9. Yin C, Han Q, Xu D, Zheng B, Zhao X, Zhang J
Oncoimmunology. 8(7):1601479. (IF 5.869)
10. Wu ZS, Yao YM, Hong GL, Xu XP, Liu Y, Dong N, Zheng JY, Lu ZQ, Zhao GJ, Zhu XM, Zhang QH, Sheng ZY.
CELL PHYSIOL BIOCHEM 2014;33(3):769-83. (IF 5.5)
11. Wang Z, Guo L, Song Y, Zhang Y, Lin D, Hu B, Mei Y, Sandikin D, Liu H.
CANCER IMMUNOL IMMUN 2017 Apr;66(4):537-548. (IF 5.442)
12. Huang FJ, Ma YL, Tang RY, Gong WC, Li J, Chen CX, Yin L, Chen XP.
Immunology 2016 Oct;149(2):238-51. (IF 5.016)
13. Yu Y, Liu L, Wang X, Liu X, Liu X, Xie L, Wang G.
Biochem Pharmacol 2010;79(7):1000-6. (IF 4.96)
15. Ma L, Li J, Wang G, Gong S, Zhang L, Li K, Ji X, Liu Y, Chen P, Xiang X.
REGUL PEPTIDES 2013 Feb 10;181:9-16. (IF 1.813)
16. Hao Y, Ren J, Liu J, Yang Z, Liu C, Li R, Su Y.
Toxicology 2013 Jul 5;309:81-90. (IF 4.099)
18. Liu Y, Cai Y, Dai L, Chen G, Ma X, Wang Y, Xu T, Jin S, Wu X, Qiu H, Tang X, Li C, Sun A, Wu D, Liu H.
Biology of blood and marrow transplantation 2013 Oct;19(10):1421-9. (IF 3.599)
20. Wang D, Guo D, Bi H, Wu Q, Tian Q, Du Y.
Toxicol In Vitro 2013 Dec;27(8):2117-26. (IF 2.959)
21. Liu W, Cai MJ, Zheng CC, Wang JX, Zhao XF.
J Biol Chem 2014 May 9;289(19):13026-41. (IF 4.238)
22. He J, Shi W, Guo Y, Chai Z.
FEBS Lett 2014 Jun 5;588(12):2087-94. (IF 3.057)
23. Guo D, Du Y, Wu Q, Jiang W, Bi H.
Arch Biochem Biophys 2014 Oct 15;560:44-51. (IF 3.391)
24. Ren J, Li XR, Liu PC, Cai MJ, Liu W, Wang JX, Zhao XF.
J STEROID BIOCHEM 2014 Oct;144 Pt B:313-23. (IF 3.813)
25. Wu Q, Guo D, Du Y, Liu D, Wang D, Bi H.
Photochem Photobiol 2014 Nov-Dec;90(6):1324-31. (IF 2.721)
26. Wang Q, Li L, Li CY, Pei Z, Zhou M, Li N.
Neuroscience 2015 Feb 12;286:109-21. (IF 3.056)
27. Hu Y, Wu L, Wang C, Luo J, Liao F, Tan H, He H.
BMC Immunol 2015 Sep 3;16:53. (IF 2.495)
28. Li J, Yue L, Wang H, Liu C, Liu H, Tao J, Qi W, Wang Y, Zhang W, Fu R, Shao Z.
J Immunol Res 2016;2016:9404705. (IF 3.327)
29. Tian X, Chang L, Ma G, Wang T, Lv M, Wang Z, Chen L, Wang Y, Gao X, Zhu Y.
Biol Pharm Bull 2016;39(2):181-91. (IF 1.863)
31. Luo T, Hu J, Xi D, Xiong H, He W, Liu J, Li M, Lu H, Zhao J, Lai W, Guo Z.
J Immunol 2016 Nov 15;197(10):3861-3870. (IF 4.886)
32. Jiang H, Zhang C, Tang Y, Zhao J, Wang T, Liu H, Sun X.
J Neurochem 2017 Jan;140(2):307-319. (IF 4.066)
33. Jiang H, Zhang C, Tang Y, Zhao J, Wang T, Liu H, Sun X.
J Neurochem 2017 Jan;140(2):307-319. (IF 4.066)
34. Zhang C, Jiang H, Wang P, Liu H, Sun X.
SCI REP-UK 2017 Mar 20;7:44708. (IF 3.998)
36. Sui HX, Ke SZ, Xu DD, Lu NN, Wang YN, Zhang YH, Gao FG.
Int J Oncol 2017 Sep;51(3):987-995. (IF 3.899)
37. Weng C, Chong L, Jia X, Zheng R, Huang Y, Zhu T, Li C, Zhang W.
Inflammation 2017 Dec;40(6):1975-1982. (IF 3.212)
38. Xu XP, Yao YM, Zhao GJ, Wu ZS, Li JC, Jiang YL, Lu ZQ, Hong GL
CHINESE MED J-PEKING 2018 Feb 5;131(3):330-338. (IF 1.585)
39. Li Y, Wang Y, Liu H, Ding K, Hao S, Shao Y, Wang H, Chen J, Huang L, Shao Z, Fu R.
Mol Med Rep 2018 Feb;17(2):2973-2981. (IF 2.1)
40. Xu XP, Yao YM, Zhao GJ, Wu ZS, Li JC, Jiang YL, Lu ZQ, Hong GL.
CHINESE MED J-PEKING 2018 Feb 5;131(3):330-338. (IF 1.585)
41. Guo HX, Ye N, Yan P, Qiu MY, Zhang J, Shen ZG, He HY, Tian ZQ, Li HL, Li JT
WORLD J GASTROENTERO 2018 Apr 28;24(16):1779-1794. (IF 3.665)
42. Li Y, Yang T, Yao Q, Li S, Fang E, Li Y, Liu C, Li W
NEUROGASTROENT MOTIL. 31(5):e13556. (IF 2.946)
43. Gao H, Chen J, Ding F, Chou X, Zhang X, Wan Y, Hu J, Wu Q
J Appl Toxicol. 39(8):1096-1107. (IF 2.997)
44. Zheng B, Yang Y, Han Q, Yin C, Pan Z, Zhang J
J Leukoc Biol. 106(4):987-996.
45. Chen J, Liu H, Li L, Wang H, Li Y, Wang Y, Ding K, Hao S, Shao Y, Li L, Song J, Wang G, Shao Z, Fu R
Mol Med Rep. 20(5):3979-3990. (IF 2.1)
46. Hui-Min Shan, Minhua Zang, Qi Zhang, Ru-Bing Shi, Xiao-Jing Shi, Muyassar Mamtilahun, Chang Liu, Long-Long Luo, Xiaoying Tian, Zhijun Zhang, Guo-Yuan Yang, Yaohui Tang, Jun Pu, Yongting Wang
J Neuroinflammation. doi: 10.1186/s12974-020-01838-w.
47. Ying Xin, Jie Gao, Rong Hu, Hong Li, Qian Li, Feng Han, Zhixu He, Laijun Lai, Min Su
Immunol Lett. doi: 10.1016/j.imlet.2020.05.005. (IF 3.276)
48. Jingyi Yang, Maohua Zhong, Ke Hong, Qingyu Yang, Ejuan Zhang, Dihan Zhou, Jianbo Xia, Yao-Qing Chen, Mingbo Sun, Bali Zhao, Jie Xiang, Ying Liu, Yang Han, Mengxin Xu, Xi Zhou, Chaolin Huang, You Shang, Huimin Yan
Clin Transl Immunology. doi: 10.1002/cti2.1259.
49. Youkun Bi, Yan Chang, Qun Liu, Yang Mao, Kui Zhai, Yuanli Zhou, Renjie Jiao, Guangju Ji
Aging (Albany NY). doi: 10.18632/aging.203063.
50. Bolin Cai, Manting Ma, Jing Zhang, Zhijun Wang, Shaofen Kong, Zhen Zhou, Ling Lian, Jiannan Zhang, Juan Li, Yajun Wang, Hongmei Li, Xiquan Zhang, Qinghua Nie
Mol Ther Nucleic Acids. doi: 10.1016/j.omtn.2021.12.004.
51. Yanyan Yi, Kangkang Gao, Pengfei Lin, Huatao Chen, Dong Zhou, Keqiong Tang, Aihua Wang, Yaping Jin
Animals (Basel). doi: 10.3390/ani12172218.